Swing Therapeutics announced new data on the long-term durability of Stanza, a digital behavioral therapy for the treatment of fibromyalgia symptoms, at the 2025 Society of Behavioral Medicine annual meeting this week.
The study, an extension of the REACT-FM trial, followed participants for 12 months to assess the durability of benefits achieved through Stanza, an app-based therapy that uses Acceptance and Commitment Therapy, a form of cognitive behavioral therapy.
Previous research, including a randomized controlled trial published in The Lancet, has established the effectiveness of Stanza in alleviating core fibromyalgia symptoms, including pain intensity, sleep interference, and overall well-being.
The REACT-FM Extension Study enrolled 41 participants who had completed the initial trial and continued to have access to the digital ACT program at their discretion. Key outcomes measured at 12 months were compared to baseline and 12-week results.
New long-term data assessed at 12 months show that:
- The proportion of participants reporting symptom improvement on the PGIC remained stable at 80.0% at 12 months, compared to 80.6% at 12 weeks.
- The average FIQ-R improvement was 29.7% at 12 months (SE 4.7%), which was a statistically significant improvement (p<.0001) and comparable to the 32.1% improvement at 12 weeks (SE 4.0%).
- Improvements in other significant areas observed at 12 weeks were maintained at 12 months, including the symptom, function, and impact domains of FIQ-R, pain intensity and interference, sleep interference, depression (BDI-II), pain acceptance (CPAQ-8), and satisfaction with quality of life.
“These findings reflect that Stanza is not only effective in the short term—it can make a meaningful and sustainable difference for people with fibromyalgia,” said Mike Rosenbluth, CEO of Swing.
About Fibromyalgia
Fibromyalgia is a chronic pain condition that affects an estimated 10 million Americans, a majority of whom are women. The condition is characterized by widespread pain and other physical and cognitive symptoms that include fatigue, disrupted sleep, reduced physical function, memory problems and difficulty concentrating (“brain fog”), and is often accompanied by anxiety and depression.
About Swing Therapeutics and Swing Care
Swing was founded in 2019 with the goal of developing evidence-based digital treatments and virtual care services to help people with chronic illness live their best lives. Stanza is an FDA-cleared digital behavioral therapy for treatment of fibromyalgia symptoms. To learn more about Stanza, visit swingtherapeutics.com
Stanza is available by prescription through Swing Care, a specialty clinic that offers comprehensive treatment for fibromyalgia. Clinical protocols were developed by Medical Director Dr. Andrea Chadwick, a globally recognized expert in fibromyalgia care. To learn more about Swing Care, visit swing.care